| 評估類型 | 急性毒性 | 全身毒性 - 單次劑量 | 全身毒性 - 重複劑量 | 神經毒性 - 單次劑量 | 皮膚致敏 | 呼吸致敏 | 皮膚刺激 | 眼睛刺激 |
|---|---|---|---|---|---|---|---|---|
| 危害評估等級 |
非常高 |
中 |
資料不足
|
資料不足
|
資料不足
|
資料不足
|
非常高 |
非常高 |
危害診斷模組
危害診斷模組是由以下四種計算化學方法構成，所預測之毒性警示提供參考，仍須與其他資料綜合評估：
- 子結構警示
- 相似性警示
- 交叉參照
- 分類模型
| Smarts | Endpoint | Source | Author | Journal |
|---|
安全替代物
安全替代物參考目前安全替代資料庫與軟體運作邏輯，分為以下三類：
- 系統透過美國環保署 ChemView 資料庫整理各化學物工業用途，結合美國環保署更安全化學物質， 建立個別化學品安全替代物清單。化學品可能具有多個工業用途，故系統採手風琴式展開清單， 點選「建議安全替代物」標籤即可展開表格。若用途較為廣泛（例：「商業用途」），清單內可能出現 更精確之工業用途（例：「溶劑」）的安全替代物。若無資訊，可參考「依工業用途（完整清單）」進行人工篩選。
- 依工業用途區分（完整清單）。此清單為整理工業用途較安全化學物，未必可直接替代本頁化學物質。 建議使用此頁籤右上方搜尋欄過濾工業用途再行篩選，例如「抗氧化劑」。資料來源： 美國環保署更安全化學物質成分清單 Safer Chemical Ingredients List
-
依結構相似性分類，需具備：
- 由結構相似性尋找具有相似官能基之化學物質（谷本相關係數 ≥ 0.8），功能可能相近。
- 由風險評估判定為較低風險之化學物質，如等級 3、等級 4，或資料不足（U）。
- 依實際案例探討。資料來源 OECD SAAT
系統依照子結構，列出風險等級為三級（可用、但可尋求更安全替代物）、四級（安全化學物質）、與資料不足（U、無足夠資料可供判別風險等級） 說明
下載：
SCIL（CSV格式）
SCIL（XLSX格式）
ZeroPM PFAS（CSV格式）
ZeroPM PFAS（XLSX格式）
SUBSPORT+ 案例替代方案（CSV格式）
SUBSPORT+ 案例替代方案（XLSX格式）
| 名稱 | CAS | 工業用途 | 安全性 | 註解 |
|---|
此化學物不在 ZeroPM PFAS 替代方案資料庫中。
SUBSPORT+ 替代案例
SUBSPORT+ 案例資料庫中與本化學物相關的實際替代案例（英文記錄）。
| 案例 | 本化學物的角色 | 替代方案 | 產業 | 功能 | 實施狀況 | 替代理由 |
|---|---|---|---|---|---|---|
| Different ways to phase out halocarbons like dichloromethane in various applications. | 作為替代品 |
|
Scientific research and development Building and construction work General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment Manufacture of computer, electronic and optical products, electrical equipment Manufacture of fabricated metal products, except machinery and equipment Manufacture of basic metals, including alloys Manufacture of plastics products, including compounding and conversion Manufacture of rubber products | Solvent | Partial capacity — Sweden | CMR physical hazards |
| Substitution of formaldehyde in bathroom cleaning products | 被替代 |
|
Manufacture of bulk, large scale chemicals (including petroleum products) | Cleaning agent | Full capacity — 2000 in Spain | CMR skin/respiratory sensitizing other toxic effects |
| Substitution of formamide with sodium hydroxide and ethanol in denaturation of DNA in the preparation of fluorescent in situ hybridization (FISH) | 作為替代品 |
|
Health services | Other | Full capacity | CMR |
| Substitution of concentrated sodium hydroxide with sodium hydrogen carbonate for pH adjustment in pharmaceutical production. | 被替代 |
|
Manufacture of bulk, large scale chemicals (including petroleum products) Manufacture of fine chemicals Health services | pH regulating agent | Full capacity — 1990 Denmark | skin/respiratory sensitizing |
| Enzymes in pharmaceutical productions can be used for degeneration of meat and for cleaning after greasy productions as an alternative for sodium hydroxide. | 被替代 |
|
Manufacture of bulk, large scale chemicals (including petroleum products) Manufacture of fine chemicals | Cleaning agent | Full capacity — 1988, Denmark | physical hazards other reasons |
| Alternatives to hydrazine in anticorrosion treatment for boilers | 作為替代品 |
|
Electricity, steam, gas water supply and sewage treatment | Aerating and dearating agents Corrosion inhibitor Deodorizer Reducing agent | In use — France | CMR skin/respiratory sensitizing |
| Substitution of sulfochromatic mixtures | 作為替代品 |
|
Scientific research and development | Cleaning agent | CMR other toxic effects neurotoxicant | |
| Substitutions performed at the National Centre for Health Data and Disease Control in Denmark (SSI) | 作為替代品 |
|
Health services Other | Cleaning agent Dye | In use | CMR ED neurotoxicant |
| Electrochemical method for the treatment of arsenic-containing drinking water | 被替代 | 未說明 | Electricity, steam, gas water supply and sewage treatment | Adsorbent | Pilot study | CMR skin/respiratory sensitizing |
| Substitution of a dish-washing compound containing Trisodium nitrilotriacetate (NTA salt) in a hospital | 作為替代品 |
|
Other | Cleaning agent | Full capacity — 2012 | CMR skin/respiratory sensitizing |
| Alternative technology for the stabilization of secondary waste sludge from waste water treatment | 被替代 | 非化學品替代 Technology with various physical processes run concomitantly or sequentially | Electricity, steam, gas water supply and sewage treatment | Solids separation (precipitating) agent | In use | skin/respiratory sensitizing CMR |
| Magnesium hydroxide as alternative to caustic soda in biological treatment of wastewater at a chicken processing plant | 被替代 |
|
Manufacture of food products Electricity, steam, gas water supply and sewage treatment | Other | In use | skin/respiratory sensitizing |
| Traditional techniques as alternative to chemical sizing and retting of textiles fibres | 被替代 | 非化學品替代 Traditional, non-chemical processing | Manufacture of textiles, leather, fur | Other | In use |
OECD SAAT 替代方案案例
OECD SAAT 案例完整清單（不隨化學物過濾）。
| 實例探討名稱 | 連結 | 發佈日期 | 發佈單位 | 相關產品 | 敘述 |
|---|