| 評估類型 | 急性毒性 | 全身毒性 - 單次劑量 | 全身毒性 - 重複劑量 | 神經毒性 - 單次劑量 | 皮膚致敏 | 呼吸致敏 | 皮膚刺激 | 眼睛刺激 |
|---|---|---|---|---|---|---|---|---|
| 危害評估等級 |
資料不足
|
資料不足
|
資料不足
|
中 |
資料不足
|
資料不足
|
資料不足
|
資料不足
|
危害診斷模組
危害診斷模組是由以下四種計算化學方法構成，所預測之毒性警示提供參考，仍須與其他資料綜合評估：
- 子結構警示
- 相似性警示
- 交叉參照
- 分類模型
| Smarts | Endpoint | Source | Author | Journal |
|---|
安全替代物
安全替代物參考目前安全替代資料庫與軟體運作邏輯，分為以下三類：
- 系統透過美國環保署 ChemView 資料庫整理各化學物工業用途，結合美國環保署更安全化學物質， 建立個別化學品安全替代物清單。化學品可能具有多個工業用途，故系統採手風琴式展開清單， 點選「建議安全替代物」標籤即可展開表格。若用途較為廣泛（例：「商業用途」），清單內可能出現 更精確之工業用途（例：「溶劑」）的安全替代物。若無資訊，可參考「依工業用途（完整清單）」進行人工篩選。
- 依工業用途區分（完整清單）。此清單為整理工業用途較安全化學物，未必可直接替代本頁化學物質。 建議使用此頁籤右上方搜尋欄過濾工業用途再行篩選，例如「抗氧化劑」。資料來源： 美國環保署更安全化學物質成分清單 Safer Chemical Ingredients List
-
依結構相似性分類，需具備：
- 由結構相似性尋找具有相似官能基之化學物質（谷本相關係數 ≥ 0.8），功能可能相近。
- 由風險評估判定為較低風險之化學物質，如等級 3、等級 4，或資料不足（U）。
- 依實際案例探討。資料來源 OECD SAAT
系統依照子結構，列出風險等級為三級（可用、但可尋求更安全替代物）、四級（安全化學物質）、與資料不足（U、無足夠資料可供判別風險等級） 說明
下載：
SCIL（CSV格式）
SCIL（XLSX格式）
ZeroPM PFAS（CSV格式）
ZeroPM PFAS（XLSX格式）
SUBSPORT+ 案例替代方案（CSV格式）
SUBSPORT+ 案例替代方案（XLSX格式）
| 名稱 | CAS | 工業用途 | 安全性 | 註解 |
|---|
此化學物不在 ZeroPM PFAS 替代方案資料庫中。
SUBSPORT+ 替代案例
SUBSPORT+ 案例資料庫中與本化學物相關的實際替代案例（英文記錄）。
| 案例 | 本化學物的角色 | 替代方案 | 產業 | 功能 | 實施狀況 | 替代理由 |
|---|---|---|---|---|---|---|
| Neutralization of alkaline waste water with high ammonia content. | 作為替代品 |
|
Manufacture of bulk, large scale chemicals (including petroleum products) Manufacture of fine chemicals Health services Electricity, steam, gas water supply and sewage treatment | pH regulating agent | Full capacity — 1990 Denmark | ecotoxicity physical hazards |
| Replacement for hydrofluorocarbon (HFC) gases and hydrocarbons with CO2 for cooling systems | 作為替代品 |
|
Manufacture of food products Manufacture of bulk, large scale chemicals (including petroleum products) Electricity, steam, gas water supply and sewage treatment Scientific research and development | Refrigerants | Full capacity — 2008, Denmark | other reasons |
| Use of carbon dioxide as alternative for caffeine extraction | 作為替代品 |
|
Manufacture of food products | Other | In use | CMR neurotoxicant |
| Carbon dioxide as alternative to sterilization using ethylene oxide | 作為替代品 |
|
Manufacture of bulk, large scale chemicals (including petroleum products) Manufacture of food products | Biocide | In use — Germany | CMR neurotoxicant |
| Tea decaffeination with carbon dioxide as alternative to ethyl acetate extraction | 作為替代品 |
|
Manufacture of food products | Other | In use | physical hazards |
| Facade cleaning using dry ice blasting for monument restoration in Prague | 作為替代品 |
|
Building and construction work | Cleaning agent | In use — Prague | CMR |
| Cleaning of motorbike repair parts using vegetable oil esters | 被替代 |
|
General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment | Cleaning agent Solvent | In use — 2004 in Germany | other toxic effects physical hazards CMR |
| Large cooling systems for buildings and industrial plants: Chillers with natural refrigerants. | 作為替代品 |
|
Building and construction work Electricity, steam, gas water supply and sewage treatment Manufacture of rubber products Manufacture of plastics products, including compounding and conversion Other | Refrigerants | Full capacity | ecotoxicity skin/respiratory sensitizing |
| Extraction of Active Pharmaceutical Ingredients (API’s) and other active organic compounds with Supercritical Carbon Dioxide. | 作為替代品 |
|
Health services Other | Other | Full capacity | CMR physical hazards skin/respiratory sensitizing other toxic effects |
| Propylene carbonate and supercritical carbon dioxide as alternative to sulfuric acid and hydrogen peroxide in semiconductors industry | 作為替代品 |
|
Manufacture of computer, electronic and optical products, electrical equipment | Semiconductor and photovoltaic agent | In use — USA | CMR |
| Substitution of tetrachloroethylene in dry clean system by liquid carbon dioxide dry cleaning in the garment care industry | 作為替代品 |
|
Other | Cleaning agent | Full capacity — 2004 USA | CMR ED ecotoxicity |
| Supercritical carbon dioxide as alternative to hexane in herbal substances extraction | 作為替代品 |
|
Health services Other | Solvent Other | Full capacity | ED skin/respiratory sensitizing ecotoxicity PBT |
| Alternatives to Toxic, VOC, Ozone Depleting and Global Warming Energised Electrical Equipment Cleaners | 作為替代品 |
|
Scientific research and development | Cleaning agent | Full capacity | CMR skin/respiratory sensitizing ecotoxicity |
| Liquefied gases as alternative to glycol containing fluids used in fog machines | 作為替代品 |
|
Other | Other | In use | other toxic effects |
| Environmental-friendly textile cleaning using wet cleaning or carbon dioxide | 作為替代品 |
|
Other | Other | In use | CMR |
| Substitution of sulphuric acid used for re-pulping process in a paper company | 作為替代品 |
|
Manufacture of textiles, leather, fur Manufacture of pulp, paper and paper products Electricity, steam, gas water supply and sewage treatment | pH regulating agent | In use | skin/respiratory sensitizing other toxic effects |
OECD SAAT 替代方案案例
OECD SAAT 案例完整清單（不隨化學物過濾）。
| 實例探討名稱 | 連結 | 發佈日期 | 發佈單位 | 相關產品 | 敘述 |
|---|