危害診斷模組
危害診斷模組是由以下四種計算化學方法構成，所預測之毒性警示提供參考，仍須與其他資料綜合評估：
- 子結構警示
- 相似性警示
- 交叉參照
- 分類模型
| Smarts | Endpoint | Source | Author | Journal |
|---|
安全替代物
安全替代物參考目前安全替代資料庫與軟體運作邏輯，分為以下三類：
- 系統透過美國環保署 ChemView 資料庫整理各化學物工業用途，結合美國環保署更安全化學物質， 建立個別化學品安全替代物清單。化學品可能具有多個工業用途，故系統採手風琴式展開清單， 點選「建議安全替代物」標籤即可展開表格。若用途較為廣泛（例：「商業用途」），清單內可能出現 更精確之工業用途（例：「溶劑」）的安全替代物。若無資訊，可參考「依工業用途（完整清單）」進行人工篩選。
- 依工業用途區分（完整清單）。此清單為整理工業用途較安全化學物，未必可直接替代本頁化學物質。 建議使用此頁籤右上方搜尋欄過濾工業用途再行篩選，例如「抗氧化劑」。資料來源： 美國環保署更安全化學物質成分清單 Safer Chemical Ingredients List
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依結構相似性分類，需具備：
- 由結構相似性尋找具有相似官能基之化學物質（谷本相關係數 ≥ 0.8），功能可能相近。
- 由風險評估判定為較低風險之化學物質，如等級 3、等級 4，或資料不足（U）。
- 依實際案例探討。資料來源 OECD SAAT
系統依照子結構，列出風險等級為三級（可用、但可尋求更安全替代物）、四級（安全化學物質）、與資料不足（U、無足夠資料可供判別風險等級） 說明
下載：
SCIL（CSV格式）
SCIL（XLSX格式）
ZeroPM PFAS（CSV格式）
ZeroPM PFAS（XLSX格式）
SUBSPORT+ 案例替代方案（CSV格式）
SUBSPORT+ 案例替代方案（XLSX格式）
| 名稱 | CAS | 工業用途 | 安全性 | 註解 |
|---|
此化學物不在 ZeroPM PFAS 替代方案資料庫中。
SUBSPORT+ 替代案例
SUBSPORT+ 案例資料庫中與本化學物相關的實際替代案例（英文記錄）。
| 案例 | 本化學物的角色 | 替代方案 | 產業 | 功能 | 實施狀況 | 替代理由 |
|---|---|---|---|---|---|---|
| Removal of trichloroethylene in the manufacture of metal parts | 被替代 | 非化學品替代 Water-based cleaning machine. Non-toxic cleaning agent (96% deionised water). | Manufacture of fabricated metal products, except machinery and equipment General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment | Cleaning agent | Full capacity — Spain | CMR other toxic effects ecotoxicity physical hazards |
| Substitution of trichloroethylene in a vocational training facility specialized in printing processes | 被替代 |
|
Printing and reproduction of recorded media Other | Cleaning agent | Full capacity — 2006, Spain | CMR neurotoxicant |
| Elimination of perchlorethylene used for dry cleaning in a laundry establishment | 被替代 | 非化學品替代 The process was modified. Perchloroethylene was used to remove stains that would not wash away with regular laundering. Given the risk it implied the use of this chemical for workers? health, this phase of the process was eliminated. Heavily stained garment pieces are discarded and replaced by new ones. The main organizational measure is eliminating the dirtiest clothes so they would not need a secondary cleaning process. | Other | Cleaning agent | In use — Spain | CMR |
| Elimination of trichloroethylene in asphalt quality control laboratories | 被替代 | 非化學品替代 Muffle furnace | Building and construction work Scientific research and development | Cleaning agent | Full capacity — 2006 en España | CMR neurotoxicant |
| Different ways to phase out halocarbons like dichloromethane in various applications. | 被替代 |
|
Scientific research and development Building and construction work General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment Manufacture of computer, electronic and optical products, electrical equipment Manufacture of fabricated metal products, except machinery and equipment Manufacture of basic metals, including alloys Manufacture of plastics products, including compounding and conversion Manufacture of rubber products | Solvent | Partial capacity — Sweden | CMR physical hazards |
| Practical guide for the substitution of hazardous chemicals by less harmful substances in industrial facilities. | 被替代 | 未說明 | Other | Other | CMR neurotoxicant skin/respiratory sensitizing physical hazards | |
| Use of carbon dioxide as alternative for caffeine extraction | 被替代 |
|
Manufacture of food products | Other | In use | CMR neurotoxicant |
| Cleaning of car steering components by injection flooding | 被替代 |
|
General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment | Cleaning agent Solvent | In use — 2004 in Germany | CMR other toxic effects |
| Micro Phase Cleaning of jet engine parts to allow crack detection | 被替代 |
|
General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment | Cleaning agent | In use — 2007 in Germany | CMR neurotoxicant |
| Alternatives to Toxic, VOC, Ozone Depleting and Global Warming Energised Electrical Equipment Cleaners | 被替代 |
|
Scientific research and development | Cleaning agent | Full capacity | CMR skin/respiratory sensitizing ecotoxicity |
| Water-based technology to produce polyurethane and polyester/polyamide microfibers | 被替代 | 非化學品替代 An alternative technology allowing complete substitution and/or elimination of different organic solvents normally used in this process. | Manufacture of textiles, leather, fur Manufacture of wood and wood products General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment Other | Other | Full capacity — Italy 2005 | CMR ED other toxic effects ecotoxicity |
| Ethyl lactate and methyl soyate as bio based alternatives to chlorinated and other petroleum based solvents | 被替代 |
|
Other | Cleaning agent Plating agent Solvent | In use | physical hazards neurotoxicant CMR ED skin/respiratory sensitizing |
| Removal of Trichloroethylene in the production of car accessories | 被替代 | 非化學品替代 Closed washing process with soap and water | General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment Manufacture of fabricated metal products, except machinery and equipment | Cleaning agent | Full capacity — 2005 in Spain | CMR neurotoxicant other toxic effects |
OECD SAAT 替代方案案例
OECD SAAT 案例完整清單（不隨化學物過濾）。
| 實例探討名稱 | 連結 | 發佈日期 | 發佈單位 | 相關產品 | 敘述 |
|---|