Searching, assessment, and screening system for safter alternative chemicals, SAS
危害診斷模組是由以下四種計算化學方法構成,所預測之毒性警示提供參考,仍須與其他資料綜合評估:
| Smarts | Endpoint | Source | Author | Journal |
|---|
安全替代物參考目前安全替代資料庫與軟體運作邏輯,分為以下三類:
系統依照子結構,列出風險等級為三級(可用、但可尋求更安全替代物)、四級(安全化學物質)、與資料不足(U、無足夠資料可供判別風險等級) 說明
| 名稱 | CAS | 工業用途 | 安全性 | 註解 |
|---|
SUBSPORT+ 案例資料庫中與本化學物相關的實際替代案例(英文記錄)。
| 案例 | 本化學物的角色 | 替代方案 | 產業 | 功能 | 實施狀況 | 替代理由 |
|---|---|---|---|---|---|---|
| Substitution of formaldehyde as a tissue fixative | 作為替代品 |
|
Health services Scientific research and development | Embalming agent | In use — France | CMR skin/respiratory sensitizing |
| Substitution of N,N-dimethylformamide with ethanol in analysis of alkaline phosphatases in leukocytes. | 作為替代品 |
|
Health services Scientific research and development | Solvent | Full capacity — 2005 in Sweden | CMR other toxic effects ecotoxicity physical hazards |
| Substitution of toluene and butan-1-ol in inks for the printing of plastic bags | 作為替代品 |
|
Manufacture of rubber products Manufacture of plastics products, including compounding and conversion | Solvent Other | Full capacity — 2007 Spain | other toxic effects ecotoxicity physical hazards |
| Substitution of epoxy resins containing naphtalene, ethylbenzene, naphta (heavy aromatic fractions) and titanium dioxide used for the painting of vehicles. | 作為替代品 |
|
General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment | Dye | In use — 2007 Spain | CMR ED neurotoxicant |
| Substitution of methanol with ethanol for use in fixation of polyacrylamide gels in analysis of proteins and DNA/RNA. | 作為替代品 |
|
Health services | Other | Full capacity — Sweden | other toxic effects |
| Mercury Assessment and Elimination in Health Care Facilities | 作為替代品 |
|
Manufacture of basic metals, including alloys | Other | In use — 1999-2000 in USA | neurotoxicant other toxic effects |
| Different ways to phase out halocarbons like dichloromethane in various applications. | 作為替代品 |
|
Scientific research and development Building and construction work General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment Manufacture of computer, electronic and optical products, electrical equipment Manufacture of fabricated metal products, except machinery and equipment Manufacture of basic metals, including alloys Manufacture of plastics products, including compounding and conversion Manufacture of rubber products | Solvent | Partial capacity — Sweden | CMR physical hazards |
| Substitution of gasoline with a combination of ethanol based all-purpose cleaner and window cleaner for cleaning of medical equipment. | 作為替代品 |
|
Scientific research and development Health services | Cleaning agent | Full capacity — Sweden | CMR physical hazards |
| Substitution of formamide with sodium hydroxide and ethanol in denaturation of DNA in the preparation of fluorescent in situ hybridization (FISH) | 作為替代品 |
|
Health services | Other | Full capacity | CMR |
| Substitution of 2-methoxyethanol with ethanol in double esterase analysis of blood samples. | 作為替代品 |
|
Health services Scientific research and development | Other | Full capacity | CMR |
| 70% ethanol as an alternative to formalin in tissue fixation | 作為替代品 |
|
Health services Scientific research and development | Durability agent Embalming agent | CMR skin/respiratory sensitizing | |
| Alternative to formaldehyde in fluid preservation of biological specimens. | 被替代 |
|
Scientific research and development | Embalming agent | Pilot study | CMR skin/respiratory sensitizing |
| Reduction of VOC emissions in windscreen washers | 被替代 |
|
Manufacture of fine chemicals | Antioxidant Cleaning agent | skin/respiratory sensitizing | |
| Alternative to formaldehyde as preservative in water samples | 作為替代品 |
|
Electricity, steam, gas water supply and sewage treatment Scientific research and development | Durability agent Embalming agent | In use — France | CMR skin/respiratory sensitizing other toxic effects physical hazards |
| Alternatives for parquet adhesive products | 被替代 |
|
Manufacture of wood and wood products Building and construction work | Sizing agent | In use — 2011 in Germany and other European countries | physical hazards |
| De-icing of car wind screens with aqueous potassium chloride solution | 被替代 |
|
Other | Antifreeze agent | 2012 | CMR neurotoxicant physical hazards |
| Shellac as alternative to bitumen in soft or hard ground etching | 作為替代品 |
|
Printing and reproduction of recorded media Other | Other | In use | CMR |
OECD SAAT 案例完整清單(不隨化學物過濾)。
| 實例探討名稱 | 連結 | 發佈日期 | 發佈單位 | 相關產品 | 敘述 |
|---|