Searching, Assessment, and Screening system for safer alternative chemicals

Searching, assessment, and screening system for safter alternative chemicals, SAS

    e.g. Benzene, DEHP, 71-43-2, BPA, phthalate

    Chemical List

    Structure Name & CAS Data Source
    2 PubChemCID:3025

    4-Quinolinecarboxamide, 2-butoxy-N-[2-(diethylamino)ethyl]-

    85-79-0
    2
    Canadian Domestic Substances List PubChem
    + 1
    SAS Classification Model: ToxTree
    1 PubChemCID:3026

    1,2-Benzenedicarboxylic acid, dibutyl ester

    84-74-2
    1
    Canadian Domestic Substances List https://echa.europa.eu/authorisation-list
    + 21
    EU Candidate List of Substances of Very High Concern (SVHC) SVHC Prioritisation Australia GHS EU GHS Japan GHS South Korea GHS Malaysia GHS New Zealand GHS The Lancet Neurology 13(3), 330-338 EU Priority List of Endocrine Disruptors ChemSec – Substitute It Now List (SIN List) German Federal Environment Agency – Substances Hazardous to Water The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List CALSafer_candidate_chemical US NIH-reproductive & developmental monographs Computed from data of CompTox PubChem Endocrine Disruptor Lists (Danish EPA) US OSHA – TRI Carcinogens SAS Classification Model: ToxTree
    1 PubChemCID:3030

    dicamba

    1918-00-9
    1
    Australia GHS EU GHS
    + 6
    New Zealand GHS The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List PubChem US OSHA – TRI Carcinogens SAS Classification Model: ToxTree
    U PubChemCID:3033

    diclofenac

    15307-86-5
    U
    PubChem SAS Classification Model: ToxTree
    1 PubChemCID:3035

    2,2-bis(p-chlorophenyl)-1,1-dichloroethylene

    72-55-9
    1
    Japan GHS Oregon SB 737 Priority Persistent Pollutants
    + 8
    OSPAR German Federal Environment Agency – Substances Hazardous to Water The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List US EPA Integrated Risk Information System (IRIS) PubChem SAS Classification Model: ToxTree https://oehha.ca.gov/proposition-65/proposition-65-list
    1 PubChemCID:3036

    DDT

    50-29-3
    1
    https://echa.europa.eu/information-on-chemicals/pbt-vpvb-assessments-under-the-previous-eu-chemicals-legislation Australia GHS
    + 23
    EU GHS Japan GHS South Korea GHS Malaysia GHS International Agency for Research on Cancer (IARC) List The Lancet Neurology 13(3), 330-338 Oregon SB 737 Priority Persistent Pollutants OSPAR Washington State Persistent Bioaccumulative Toxins EU Priority List of Endocrine Disruptors German Federal Environment Agency – Substances Hazardous to Water The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List US EPA Integrated Risk Information System (IRIS) US HHS – 14th Report on Carcinogens US CDC – Occupational Carcinogens List Computed from data of CompTox PubChem SAS 112 diagnostic module - Read-across SAS Classification Model: ToxTree https://oehha.ca.gov/proposition-65/proposition-65-list https://chm.pops.int/TheConvention/ThePOPs/AllPOPs/tabid/2509/Default.aspx https://monographs.iarc.who.int/list-of-classifications
    1 PubChemCID:3037

    Phenol, 2,2'-methylenebis[4-chloro-

    97-23-4
    1
    Canadian Domestic Substances List Australia GHS
    + 9
    EU GHS Japan GHS New Zealand GHS The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List CALSafer_candidate_chemical PubChem US OSHA – TRI Carcinogens SAS Classification Model: ToxTree
    1 PubChemCID:3038

    Dichlorphenamide

    120-97-8
    1
    SAS Classification Model: ToxTree
    1 PubChemCID:3039

    Dichlorvos

    62-73-7
    1
    Canadian Domestic Substances List Canadian Workplace Hazardous Materials Information System 2015 (WHMIS 2015)
    + 18
    Australia GHS EU GHS Japan GHS South Korea GHS Malaysia GHS New Zealand GHS International Agency for Research on Cancer (IARC) List The Lancet Neurology 13(3), 330-338 German Federal Environment Agency – Substances Hazardous to Water The Endocrine Disruption Exchange – Potential Endocrine Disruptors List US EPA EPCRA Extremely Hazardous Substances List US EPA Integrated Risk Information System (IRIS) PubChem Silent Spring Institute - Breast Cancer Chemicals US OSHA – TRI Carcinogens SAS Classification Model: ToxTree https://oehha.ca.gov/proposition-65/proposition-65-list https://monographs.iarc.who.int/list-of-classifications
    3 PubChemCID:3042

    dicyclomine

    77-19-0
    3
    Canadian Domestic Substances List PubChem
    + 1
    SAS Classification Model: ToxTree